Jell-O® microfluidics and synthetic biology: combining science outreach with basic research
نویسندگان
چکیده
منابع مشابه
Microfluidics for Control in Synthetic Biology
We report the microfluidic control of a synthetic biological system using a one milliliter volume microbioreactor. Precise fluid injection and mixing enable control schemes such as rapid medium introduction in continuous culture conditions. A Saccharomyces cerevisiae strain with a dual inducible fluorescent reporter system was tested with the microbioreactor cultivation for precise induction co...
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Microfluidic systems with integrated analysis and control of environmental parameters can enable precise control of metabolic activity and protein expression. Here, we couple microfluidic controls in a polycarbonate-PDMS microbioreactor (Fig. 1) with closed-loop control of temperature, pH, dissolved oxygen, and cell density [1,2] to the biochemical control of synthetic gene circuits [3,4]. In s...
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This paper describes the development of a new university physics course which integrates physics education, research, and community outreach. The coordinated system of activities links the new course to local community efforts in pre-college education, university education, university outreach, and research on teaching and learning. The course was found to improve student understanding of physi...
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Synthetic biology is a rapidly growing multidisciplinary branch of science which aims to mimic complex biological systems by creating similar forms. Constructing an artificial system requires optimization at the gene and protein levels to allow the formation of entire biological pathways. Advances in cell-free synthetic biology have helped in discovering new genes, proteins, and pathways bypass...
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With the expanding interest in cellular responses to dynamic environments, microfluidic devices have become important experimental platforms for biological research. Microfluidic "microchemostat" devices enable precise environmental control while capturing high quality, single-cell gene expression data. For studies of population heterogeneity and gene expression noise, these abilities are cruci...
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ژورنال
عنوان ژورنال: Bioanalysis
سال: 2010
ISSN: 1757-6180,1757-6199
DOI: 10.4155/bio.10.123